Biote His-T – 60 Capsules

Description

What is Biote His-T?

Biote His-T is a targeted daily formula designed to support men’s healthy testosterone balance—fueling steady energy, drive, lean-body composition goals, cognitive focus, and mood—without the stimulant crash. A smart blend of supportive botanicals and key micronutrients (including zinc and other cofactors) works with the body’s natural pathways to back androgen metabolism within the normal range and promote resilience under stress. Clean, easy-to-take capsules fit seamlessly into any routine and layer well with foundational staples like a multivitamin and omega-3s, making Biote His-T a simple way to feel stronger, clearer, and more confident day to day.

Most of the published literature in men suggests that healthy testosterone levels improve clinical outcomes, ie. body composition, bone mineral density, and does not increase prostate cancer. Therefore, maintaining a healthy testosterone balance is essential in men.

biote his-t capsules bottle

In addition, research suggests that testosterone and cortisol have an inverse relationship. In other words, when cortisol is elevated, testosterone levels decrease, likely secondary to decreased hypothalamic- pituitary-gonadal (HPG) signaling,

What are the benefits of Biote His-T?

• Supports healthy testosterone balance
• Supports healthy cortisol levels
• Supports healthy nitric oxide production
• Supports prostate health
• Supports health and longevity
• Supports healthy testosterone levels
• Supports healthy stress hormone levels
• Supports nitric oxide production

Supports Multi-Mechanistic Hormone Balance:

• Selective estrogen receptor modulation (SERM)
• Prolactin
• Aromatase
• Five-alpha reductase Luteinizing hormone

What are the main ingredients of Biote His-T?

Pyridoxine (Vitamin B)

Exciting research indicates that vitamin B plays a vital role in maintaining healthy testosterone levels by balancing cortisol and prolactin. Elevated levels of both hormones can inhibit testosterone production. Fortunately, vitamin B has been shown to significantly lower prolactin and potentially modulate high cortisol levels by blocking glucocorticoid receptors. This collective action helps to enhance testosterone synthesis, paving the way for better hormonal health. Isn’t it incredible how nutrients can positively influence our bodies?

Cholecalciferol (Vitamin D)

Vitamin D is foundational for men: it drives calcium absorption for stronger bones and teeth, supports muscle strength and power output, fortifies immune defenses, and is linked to better mood, cognitive resilience, and cardiometabolic health (insulin sensitivity, healthy inflammatory balance). Adequate vitamin D also supports reproductive health—deficiency is associated with poorer sperm quality and lower testosterone, and correcting it can help normalize levels—while aiding recovery from training by supporting neuromuscular function. Because insufficiency is common (indoor work, higher latitudes, darker skin tones, sunscreen), aim for consistent intake from food, sensible sun, or supplements; take D3 with a meal containing fat, and consider pairing with magnesium and vitamin K2 to optimize calcium utilization. The available evidence in men indicates that vitamin D3, a prohormone, is associated with total and free testosterone levels, i.e., as vitamin D levels increase, so do total and free testosterone levels, and as vitamin D levels decrease, so does testosterone.  Notably, in one study vitamin D3 supplementation resulted in significantly higher total and free testosterone levels in middle-aged men.

Zinc (Zn)

Zinc is an incredible essential mineral that not only helps modulate our immune system but also plays a vital role in synthesizing luteinizing hormone (LH) and producing testosterone. When zinc levels drop, it can negatively affect LH and testosterone production, and even lead to increased expression of estrogen receptors. Excitingly, studies show that a zinc supplement of 30mg daily can nearly double testosterone levels in men facing marginal deficiency! Plus, zinc helps inhibit the enzyme 5-alpha reductase, which converts testosterone into a more potent form, 5-alpha dihydrotestosterone (DHT), and this effect is even stronger with vitamin B6!

Protodioscin

Protodioscin is an incredible steroidal saponin found in plants like those from the Melanthiaceae, Zygophyllaceae, and Fabaceae families. These fascinating plants have a rich history in Chinese and Indian medicine. Excitingly, well-controlled clinical trials show that Protodioscin can boost total testosterone levels, highlighting its potential benefits!

Secoisolariciresinol Diglucoside (SDG)

Let’s delve into the fascinating world of the lignan chemical class, particularly a remarkable phytochemical known as secoisolariciresinol diglucoside (SDG)! This powerful compound has shown remarkable promise in inhibiting aromatase, the enzyme responsible for converting testosterone into estradiol, thereby helping maintain healthy testosterone levels. Excitingly, research highlights that enterolactone, SDG’s primary metabolite, acts as a potent 5-alpha reductase inhibitor, which aids in preserving testosterone by preventing its conversion to dihydrotestosterone (DHT).

Moreover, studies suggest that SDG, especially at higher concentrations, may effectively reduce cortisol levels in response to mental stress—something we can all relate to! With the understanding that cortisol and testosterone have an inverse relationship, supporting healthy cortisol levels becomes essential for maintaining testosterone balance. Additionally, lignans like SDG work as selective estrogen receptor modulators (SERMs), contributing to the health of hormone-sensitive prostate tissue in men. The potential benefits of SDG are truly exciting!

Ursolic Acid

Ursolic acid, an exciting pentacyclic triterpenoid phytochemical, plays a fascinating role in promoting cardiovascular health! By enhancing the production of endothelial nitric oxide synthase (eNOS) in arterial walls, it helps boost nitric oxide levels, which are vital for maintaining healthy vascular function. Unfortunately, eNOS levels can decline with age, but that’s where ursolic acid shines by supporting its availability and effectiveness against harmful free radicals like superoxide.

Moreover, researchers have discovered that ursolic acid is a remarkable phosphodiesterase type 5 (PDE5) inhibitor, nearing the efficacy of vardenafil (commonly known as Levitra®). Beyond heart health, it also offers potential benefits for prostate health, significantly reducing dihydrotestosterone (DHT) levels in the serum and prostate as effectively as the well-known drug finasteride (Proscar®), which is FDA-approved for benign prostatic hypertrophy (BPH). With these promising abilities, ursolic acid truly stands out as a valuable compound for our well-being!

Spermidine

Spermidine is an incredible natural compound produced by every living cell, whether in plants or animals, playing a vital role in maintaining life. It’s fascinating to know that spermidine is the most abundant polyamine, but its levels decline as we age. Excitingly, a high dietary intake of spermidine and related polyamines has been linked to enhanced health and longevity—making it a remarkable “anti-aging” molecule! Its effects are similar to those of caloric restriction, a well-known anti-aging strategy. Furthermore, testosterone boosts spermidine production, and lower testosterone can lead to reduced levels of spermidine. Research is promising, showing that spermidine supplementation can enhance men’s testosterone levels by about 50%, while also lowering cortisol levels significantly. Isn’t that inspiring?

How do I use Biote His-T?

Take 2 capsules daily in the morning with a light meal or snack, as a dietary supplement, or as your healthcare provider recommends.

STORAGE: Store tightly sealed in a cool, dry place.

FREE FROM: Soy, Dairy, Gluten, Wheat, Egg, Corn, Tree Nuts, Peanuts, Shellfish, Fish, Sesame, Artificial Colorings or Flavorings.

What are Biote products?

Biote products offer a safe, effective, and personalized approach to nutraceuticals and hormone optimization that can unlock your full potential and ignite your inner spark.  Read more about Biote products.

How can I get started?

Are you ready to start feeling better? Getting started with Biote supplements is easy. Simply schedule an appointment with Cunningham Clinic to discuss your options and pick up your nutraceutical-grade Biote His-T supplement!  We’re happy to help you look and feel your best.