What is XYMOGEN Methyl Protect?
Methyl Protect is a comprehensive formula designed to support optimal methylation and help maintain healthy homocysteine levels already within normal range. It features five key nutrients that are involved in homocysteine metabolism: folate as calcium folinate and Quatrefolic® for increased bioactivity; trimethylglycine; and vitamins B12, B6, and B2. These five nutrients, provided in activated forms, support enhanced methylation and overall cardiovascular health.
What are the benefits?
What is Methylation?
Methylation is the addition of a methyl group (a carbon atom with three hydrogen atoms attached) to proteins, enzymes, chemicals, DNA, or amino acids like homocysteine. It is a vital and fundamental process that takes place in many biochemical pathways involving detoxification, cardiovascular health, neurological health, eye health, muscle health, bone health, and redox balance. Effective methylation also has roles in the biosynthesis and breakdown of catecholamines, such as epinephrine. This is an important aspect of healthy adrenal functioning.
What is in XYMOGEN Methyl Protect?
Folic Acid (as calcium folinate and 5-methyltetrahydrofolate) – This B vitamin has important roles in detoxification, nervous system function, breast tissue health, prenatal development, and the conversion of homocysteine back to methionine. In its active form, folic acid serves as a donor of methyl groups. Providing the combination of calcium folinate and 5-methyltetrahydrofolate (5- MTHF) allows optimal utilization of folic acid by bypassing metabolic steps to bioactivity. In fact, 5-MTHF is the form into which the body must convert all other forms of folic acid before it can be used. In this formula, 5-MTHF is provided as calcium folinate and Quatrefolic®. Quatrefolic is proven to have greater stability, solubility, and bioavailability over the calcium salt forms of 5-MTHF.
Trimethylglycine (as anhydrous betaine) – Found in several tissues in humans, trimethylglycine acts as an alternative methyl donor in homocysteine metabolism. Trimethylglycine may also be a preventive agent against the activation of NF-kappaB.
Vitamin B12 (as methylcobalamin) – Cyanocobalamin (the form of B12 present in many supplements) has to be converted in the liver to methylcobalamin, the form provided in Methyl Protect. B12 is another methyl donor, and studies suggest that it supports healthy homocysteine levels already within the normal range on its own and in combination with folate.
Vitamin B6 (as pyridoxal 5’-phosphate) – This coenzyme form of vitamin B6 is the primary bioactive form. It is a coenzyme in approximately 100 enzymatic reactions. Data from the Framingham Study showed an inverse association between homocysteine and good B6 status (as well as B12 and folate).
Vitamin B2 (as riboflavin 5’-phosphate) – As the principal coenzyme form of B2, riboflavin 5’-phosphate is used in many oxidative reactions. Folate and riboflavin interact to support healthy homocysteine levels already within the normal range, possibly by maximizing the catalytic activity of the enzyme methylenetetrahydrofolate reductase (MTHFR). The effect may be unrelated to MTHFR genotype.
What are XYMOGEN products?
Xymogen products are science-backed supplements designed to support your overall health and well-being. Discover how Xymogen products can help you achieve your health goals. Read more about XYMOGEN products.
How can I get started with XYMOGEN Methyl Protect?
Are you ready to start feeling better? Starting with Methyl Protect is easy. Simply schedule an appointment with Cunningham Clinic, discuss your concerns with your provider and then pick up your nutraceutical grade Methyl Protect.