SkinMedica TNS Advanced+ Serum®

(19 customer reviews)

$295.00 See sale price in cart or just $236.00 with a subscription

An age-defying, proprietary blend that uniquely supports healthy skin functions to produce skin that’s revitalized.

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What is the difference between SkinMedica TNS Advanced+ Serum and TNS Essential Serum?

Skinmedica TNS Advanced+ Serum is the next-generation, skin-renewing formula that improves the appearance of coarse wrinkles, fine lines, skin tone, and texture. It’s the only growth factor product proven to address sagging skin, leveraging the combination of growth factor research and SkinMedica science. The first chamber contains TNS-MR.  It’s a highly concentrated growth factor blend with over 450 natural growth factors and other proteins. The second chamber contains RENESSENSCE (RSC) Advanced.  It’s an active blend of botanicals, marine extracts, and peptides that assist the growth factor blend in skin rejuvenation.  These two formulas work together, providing results faster than ever before.  Visible results may be evident in as little as 2 weeks.

This technology creates the differences between TNS Essential Serum and TNS Advanced+ Serum:

  • It provides faster results. Testing shows that results may be evident in as little as 2 weeks.
  • It also provides targeted treatment for challenging areas. TNS Advanced+ Serum provides our most comprehensive skin benefits.
  • It’s also our only growth factor serum proven to address sagging skin.
  • It’s also colorless and fragrance-free.


How does the new technology address sagging skin?

TNS-MR supports the structural proteins of the skin at all levels.  As a result TNS Advanced+ Serum can visibly lift the appearance of sagging skin in as soon as 8 weeks.  In a third-party study, patients also felt they looked up to 6 years younger after 12 weeks.

What’s Inside?

Chamber 1: TNS-MR (Human fibroblast conditioned media) – This advanced formula acts on mulitple levels to help get you to age-defying results:

  • Next generation growth factor blend, supporting healthy skin functions.
  • Innovative peptide complex to nourish your skin.


Chamber 2: RENESSENCE (RSC) ADVANCED  – A highly active blend of botanicals, marine extracts, and peptides.  It amplifies the effects of the growth factor chamber:

  • French flax seed extract, to support repair functions.
  • Spanish marine extracts, to support skin’s renewal process.
  • Green microalgae, to support collagen and elastin levels.


It’s an age-defying, proprietary blend that uniquely supports healthy skin functions to produce skin that’s revitalized. SkinMedica TNS Advanced+ Serum is made with growth factor technology, backed up with RENESSENSCE (RSC) Advanced, designed to bolster the results.


What are the benefits of SkinMedica TNS Advanced+ Serum?

    • Smooths coarse wrinkles and fine lines.
    • Lifts sagging skin.
    • Evens the appearance of skin tone and texture.
    • Colorless and fragrance-free.


What is a growth factor?

It’s a natural substance made by skin cells, that plays a pivotal role in maintaining skin’s firmness and elasticity. SkinMedica TNS Advanced+ Serum is made with growth factor technology, backed up with RENESSENSCE (RSC) Advanced, specifically designed to
bolster results.

Priming your TNS Advanced+ Serum and Troubleshooting:

TNS Advanced+ Serum is a dual-chamber product, which requires priming the bottle and sometimes some troubleshootingThese techniques will help ensure you get the most out of your Serum.

How can I get started?

Are you ready to reduce the appearance of fine lines and wrinkles, enhance skin texture and skin tone? Starting with TNS Advanced+ Serum is easy. First, apply in the morning and evening.  Apply to your entire face (neck and also chest if desired).  Order online and watch for results in as soon as just two weeks!

To apply, dispense on the back of your hand.  Always blend together before applying to skin. Importantly, avoid getting in eyes. If contact occurs, rinse eyes thoroughly with water.   Colorless, fragrance-free, lightweight, matte finish.  Appropriate for all skin types. Get the most out of your skin care routine by learning the best order to apply your SkinMedica products in.

Cunningham Clinic is an authorized reseller of SkinMedica products. When you purchase from us, you can be confident that each product is authentic without worrying about counterfeit products.

How can I earn Allē (Formerly Brilliant Distinctions) Points?

Allē is a rewards program that helps you save on SkinMedica.    Learn about Alle Points, and register to start earning and saving! You can also login and check your account status any time.

Then, log in to your Allē account  and retrieve the cell phone number you used to register. Once you’ve ordered with us and entered your Allē cell phone number, it will be saved to your account when you register with Cunningham Clinic.

What else can I do to age healthier and live happier?

Simply schedule an appointment with Cunningham Clinic to discuss your options.  We’re happy to help you look and feel your best.

Interested in saving more on SkinMedica TNS Advanced+ Serum?  This fantastic product is also available in a money-saving bundle with two other award-winning products.

What makes SkinMedica different from other skin care brands?

A lot of products on the market are driven by marketing. This might sound familiar: You see a new serum on the shelf of your favorite beauty retailer, and it lures you in with cute packaging and an interesting story or celebrity brand founder. But, when you bring it home and actually use it, you see little more than a quick fix. That’s not what SkinMedica is about. Every product in this line is driven by science, to help improve the appearance of your skin both instantly and over time.


Water/Aqua/Eau, Pentylene Glycol, Human Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Trifluoroacetyl Tripeptide-2, Dimer Tripeptide-43, Hydrolyzed Linseed Extract, Vitis Vinifera (Grape) Flower Cell Extract, Pyrus Malus (Apple) Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Dextran, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin

Additional information

Weight 8.3 oz
Dimensions 3 × 3 × 8 in
Choose one-time or subscription

Every 2 Months, Every 3 Months, Every 4 Months, Every 6 Months, Every Month, One-Time

19 reviews for SkinMedica TNS Advanced+ Serum®

  1. Dahlia (verified owner)

    SkinMedica TNS Advanced Serum – my friends noticed the difference! Really helps with fine lines

    Delivery: Product shipped the next day, and arrived in three days. As advertised.

  2. Alix (verified owner)


  3. LitaD (verified owner)

    TNS A+ is my every morning and evening routine.

  4. LitaD (verified owner)

  5. Candy (verified owner)

    TNS Advanced is simply the best growth factor product out there – and I have tried several.

  6. KellyR (verified owner)

    SkinMedica TNS Advanced – I tried it after seeing the awards. It’s worth it!

  7. Elena (verified owner)

    TNS Advanced was recommended by my dermatologist as the most effective serum. I’ve been using it for six months now and the difference in my fine lines and skin texture makes it totally worth it!

  8. Hudson (verified owner)

    I’ve been using SkinMedica for months now, and the improvement in my skin’s texture is remarkable.

  9. Tricia (verified owner)

  10. Holly (verified owner)

    This serum arrived right on time – and the price was better than most.

  11. Ellen (verified owner)

  12. NinaC (verified owner)

    This stuff is simply great – thanks Skinmedica

  13. AdriannaM (verified owner)

    An essential foundation for anyone’s skincare regime, regardless of age.

  14. Gerri (verified owner)

    SkinMedica TNS rocks.

  15. Roxy (verified owner)

    The person who took my call knew all about TNS Advanced – bvery helpful advice. Thanks!

  16. Iona (verified owner)

    Excellent for my wrinkles and the fine lines around my eyes. Crows feet have never looked better – not since I was 40. Should have started sooner.

  17. Holly (verified owner)

  18. Hailey (verified owner)

    Every application makes my skin feel pampered and cared for.

  19. JackieR (verified owner)

    Great price – arrived fast.

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